Meprosan

Meprosan Brand names, Meprosan Analogs

Meprosan Brand Names Mixture

No information avaliable

Meprosan Chemical_Formula

C₂₀H₂₃NS

Meprosan RX_link

No information avaliable

Meprosan fda sheet

Meprosan msds (material safety sheet)

Meprosan Synthesis Reference

No information avaliable

Meprosan Molecular Weight

309.469 g/mol

Meprosan Melting Point

< 25 ^oC

Meprosan H₂O Solubility

Soluble as HCl salt

Meprosan State

Liquid

Meprosan LogP

5.7

Meprosan Dosage Forms

Tablets (oral, 1 mg)

Meprosan Indication

Used for the symptomatic treatment of parkinsonism.

Meprosan Pharmacology

Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.

Meprosan Absorption

Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.

Meprosan side effects and Toxicity

Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Meprosan Patient Information

Meprosan Organisms Affected

Humans and other mammals