Mar-Bate

Mar-Bate Brand names, Mar-Bate Analogs

Mar-Bate Brand Names Mixture

No information avaliable

Mar-Bate Chemical_Formula

C₂₀H₂₃NS

Mar-Bate RX_link

No information avaliable

Mar-Bate fda sheet

Mar-Bate msds (material safety sheet)

Mar-Bate Synthesis Reference

No information avaliable

Mar-Bate Molecular Weight

309.469 g/mol

Mar-Bate Melting Point

< 25 ^oC

Mar-Bate H₂O Solubility

Soluble as HCl salt

Mar-Bate State

Liquid

Mar-Bate LogP

5.7

Mar-Bate Dosage Forms

Tablets (oral, 1 mg)

Mar-Bate Indication

Used for the symptomatic treatment of parkinsonism.

Mar-Bate Pharmacology

Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.

Mar-Bate Absorption

Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.

Mar-Bate side effects and Toxicity

Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Mar-Bate Patient Information

Mar-Bate Organisms Affected

Humans and other mammals