Perquietil
Brand names,
Perquietil
Analogs
Perquietil
Brand Names Mixture
Perquietil
Chemical_Formula
C20H23NS
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RX_link
No information avaliable
Perquietil
fda sheet
Perquietil
msds (material safety sheet)
Perquietil
Synthesis Reference
No information avaliable
Perquietil
Molecular Weight
309.469 g/mol
Perquietil
Melting Point
< 25 oC
Perquietil
H2O Solubility
Soluble as HCl salt
Perquietil
State
Liquid
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LogP
5.7
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Dosage Forms
Tablets (oral, 1 mg)
Perquietil
Indication
Used for the symptomatic treatment of parkinsonism.
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Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Perquietil
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Perquietil
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Perquietil
Patient Information
Perquietil
Organisms Affected
Humans and other mammals