Meprodiol
Brand names,
Meprodiol
Analogs
Meprodiol
Brand Names Mixture
Meprodiol
Chemical_Formula
C20H23NS
Meprodiol
RX_link
No information avaliable
Meprodiol
fda sheet
Meprodiol
msds (material safety sheet)
Meprodiol
Synthesis Reference
No information avaliable
Meprodiol
Molecular Weight
309.469 g/mol
Meprodiol
Melting Point
< 25 oC
Meprodiol
H2O Solubility
Soluble as HCl salt
Meprodiol
State
Liquid
Meprodiol
LogP
5.7
Meprodiol
Dosage Forms
Tablets (oral, 1 mg)
Meprodiol
Indication
Used for the symptomatic treatment of parkinsonism.
Meprodiol
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Meprodiol
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Meprodiol
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Meprodiol
Patient Information
Meprodiol
Organisms Affected
Humans and other mammals