Restenyl
Brand names,
Restenyl
Analogs
Restenyl
Brand Names Mixture
Restenyl
Chemical_Formula
C20H23NS
Restenyl
RX_link
No information avaliable
Restenyl
fda sheet
Restenyl
msds (material safety sheet)
Restenyl
Synthesis Reference
No information avaliable
Restenyl
Molecular Weight
309.469 g/mol
Restenyl
Melting Point
< 25 oC
Restenyl
H2O Solubility
Soluble as HCl salt
Restenyl
State
Liquid
Restenyl
LogP
5.7
Restenyl
Dosage Forms
Tablets (oral, 1 mg)
Restenyl
Indication
Used for the symptomatic treatment of parkinsonism.
Restenyl
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Restenyl
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Restenyl
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Restenyl
Patient Information
Restenyl
Organisms Affected
Humans and other mammals