Ansil
Brand names,
Ansil
Analogs
Ansil
Brand Names Mixture
Ansil
Chemical_Formula
C20H23NS
Ansil
RX_link
No information avaliable
Ansil
fda sheet
Ansil
msds (material safety sheet)
Ansil
Synthesis Reference
No information avaliable
Ansil
Molecular Weight
309.469 g/mol
Ansil
Melting Point
< 25 oC
Ansil
H2O Solubility
Soluble as HCl salt
Ansil
State
Liquid
Ansil
LogP
5.7
Ansil
Dosage Forms
Tablets (oral, 1 mg)
Ansil
Indication
Used for the symptomatic treatment of parkinsonism.
Ansil
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Ansil
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Ansil
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Ansil
Patient Information
Ansil
Organisms Affected
Humans and other mammals