Mepantin
Brand names,
Mepantin
Analogs
Mepantin
Brand Names Mixture
Mepantin
Chemical_Formula
C20H23NS
Mepantin
RX_link
No information avaliable
Mepantin
fda sheet
Mepantin
msds (material safety sheet)
Mepantin
Synthesis Reference
No information avaliable
Mepantin
Molecular Weight
309.469 g/mol
Mepantin
Melting Point
< 25 oC
Mepantin
H2O Solubility
Soluble as HCl salt
Mepantin
State
Liquid
Mepantin
LogP
5.7
Mepantin
Dosage Forms
Tablets (oral, 1 mg)
Mepantin
Indication
Used for the symptomatic treatment of parkinsonism.
Mepantin
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Mepantin
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Mepantin
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Mepantin
Patient Information
Mepantin
Organisms Affected
Humans and other mammals