Zirpon
Brand names,
Zirpon
Analogs
Zirpon
Brand Names Mixture
Zirpon
Chemical_Formula
C20H23NS
Zirpon
RX_link
No information avaliable
Zirpon
fda sheet
Zirpon
msds (material safety sheet)
Zirpon
Synthesis Reference
No information avaliable
Zirpon
Molecular Weight
309.469 g/mol
Zirpon
Melting Point
< 25 oC
Zirpon
H2O Solubility
Soluble as HCl salt
Zirpon
State
Liquid
Zirpon
LogP
5.7
Zirpon
Dosage Forms
Tablets (oral, 1 mg)
Zirpon
Indication
Used for the symptomatic treatment of parkinsonism.
Zirpon
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Zirpon
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Zirpon
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Zirpon
Patient Information
Zirpon
Organisms Affected
Humans and other mammals