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Mepiosine Brand names, Mepiosine Analogs

Mepiosine Brand Names Mixture

  • No information avaliable

Mepiosine Chemical_Formula


Mepiosine RX_link

No information avaliable

Mepiosine fda sheet

Mepiosine msds (material safety sheet)

Mepiosine Synthesis Reference

No information avaliable

Mepiosine Molecular Weight

309.469 g/mol

Mepiosine Melting Point

< 25 oC

Mepiosine H2O Solubility

Soluble as HCl salt

Mepiosine State


Mepiosine LogP


Mepiosine Dosage Forms

Tablets (oral, 1 mg)

Mepiosine Indication

Used for the symptomatic treatment of parkinsonism.

Mepiosine Pharmacology

Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.

Mepiosine Absorption

Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.

Mepiosine side effects and Toxicity

Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Mepiosine Patient Information

Mepiosine Organisms Affected

Humans and other mammals