Meprospan
Brand names,
Meprospan
Analogs
Meprospan
Brand Names Mixture
Meprospan
Chemical_Formula
C20H23NS
Meprospan
RX_link
No information avaliable
Meprospan
fda sheet
Meprospan
msds (material safety sheet)
Meprospan
Synthesis Reference
No information avaliable
Meprospan
Molecular Weight
309.469 g/mol
Meprospan
Melting Point
< 25 oC
Meprospan
H2O Solubility
Soluble as HCl salt
Meprospan
State
Liquid
Meprospan
LogP
5.7
Meprospan
Dosage Forms
Tablets (oral, 1 mg)
Meprospan
Indication
Used for the symptomatic treatment of parkinsonism.
Meprospan
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Meprospan
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Meprospan
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Meprospan
Patient Information
Meprospan
Organisms Affected
Humans and other mammals