Placidon

Placidon Brand names, Placidon Analogs

Placidon Brand Names Mixture

No information avaliable

Placidon Chemical_Formula

C₂₀H₂₃NS

Placidon RX_link

No information avaliable

Placidon fda sheet

Placidon msds (material safety sheet)

Placidon Synthesis Reference

No information avaliable

Placidon Molecular Weight

309.469 g/mol

Placidon Melting Point

< 25 ^oC

Placidon H₂O Solubility

Soluble as HCl salt

Placidon State

Liquid

Placidon LogP

5.7

Placidon Dosage Forms

Tablets (oral, 1 mg)

Placidon Indication

Used for the symptomatic treatment of parkinsonism.

Placidon Pharmacology

Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.

Placidon Absorption

Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.

Placidon side effects and Toxicity

Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Placidon Patient Information

Placidon Organisms Affected

Humans and other mammals