Tranquillin
Brand names,
Tranquillin
Analogs
Tranquillin
Brand Names Mixture
Tranquillin
Chemical_Formula
C20H23NS
Tranquillin
RX_link
No information avaliable
Tranquillin
fda sheet
Tranquillin
msds (material safety sheet)
Tranquillin
Synthesis Reference
No information avaliable
Tranquillin
Molecular Weight
309.469 g/mol
Tranquillin
Melting Point
< 25 oC
Tranquillin
H2O Solubility
Soluble as HCl salt
Tranquillin
State
Liquid
Tranquillin
LogP
5.7
Tranquillin
Dosage Forms
Tablets (oral, 1 mg)
Tranquillin
Indication
Used for the symptomatic treatment of parkinsonism.
Tranquillin
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Tranquillin
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Tranquillin
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Tranquillin
Patient Information
Tranquillin
Organisms Affected
Humans and other mammals