Epicur
Brand names,
Epicur
Analogs
Epicur
Brand Names Mixture
Epicur
Chemical_Formula
C20H23NS
Epicur
RX_link
No information avaliable
Epicur
fda sheet
Epicur
msds (material safety sheet)
Epicur
Synthesis Reference
No information avaliable
Epicur
Molecular Weight
309.469 g/mol
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Melting Point
< 25 oC
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H2O Solubility
Soluble as HCl salt
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State
Liquid
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LogP
5.7
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Dosage Forms
Tablets (oral, 1 mg)
Epicur
Indication
Used for the symptomatic treatment of parkinsonism.
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Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Epicur
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Epicur
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Epicur
Patient Information
Epicur
Organisms Affected
Humans and other mammals