Fas-Cile
Brand names,
Fas-Cile
Analogs
Fas-Cile
Brand Names Mixture
Fas-Cile
Chemical_Formula
C20H23NS
Fas-Cile
RX_link
No information avaliable
Fas-Cile
fda sheet
Fas-Cile
msds (material safety sheet)
Fas-Cile
Synthesis Reference
No information avaliable
Fas-Cile
Molecular Weight
309.469 g/mol
Fas-Cile
Melting Point
< 25 oC
Fas-Cile
H2O Solubility
Soluble as HCl salt
Fas-Cile
State
Liquid
Fas-Cile
LogP
5.7
Fas-Cile
Dosage Forms
Tablets (oral, 1 mg)
Fas-Cile
Indication
Used for the symptomatic treatment of parkinsonism.
Fas-Cile
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Fas-Cile
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Fas-Cile
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Fas-Cile
Patient Information
Fas-Cile
Organisms Affected
Humans and other mammals