Restinil
Brand names,
Restinil
Analogs
Restinil
Brand Names Mixture
Restinil
Chemical_Formula
C20H23NS
Restinil
RX_link
No information avaliable
Restinil
fda sheet
Restinil
msds (material safety sheet)
Restinil
Synthesis Reference
No information avaliable
Restinil
Molecular Weight
309.469 g/mol
Restinil
Melting Point
< 25 oC
Restinil
H2O Solubility
Soluble as HCl salt
Restinil
State
Liquid
Restinil
LogP
5.7
Restinil
Dosage Forms
Tablets (oral, 1 mg)
Restinil
Indication
Used for the symptomatic treatment of parkinsonism.
Restinil
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Restinil
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Restinil
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Restinil
Patient Information
Restinil
Organisms Affected
Humans and other mammals