Biobamat
Brand names,
Biobamat
Analogs
Biobamat
Brand Names Mixture
Biobamat
Chemical_Formula
C20H23NS
Biobamat
RX_link
No information avaliable
Biobamat
fda sheet
Biobamat
msds (material safety sheet)
Biobamat
Synthesis Reference
No information avaliable
Biobamat
Molecular Weight
309.469 g/mol
Biobamat
Melting Point
< 25 oC
Biobamat
H2O Solubility
Soluble as HCl salt
Biobamat
State
Liquid
Biobamat
LogP
5.7
Biobamat
Dosage Forms
Tablets (oral, 1 mg)
Biobamat
Indication
Used for the symptomatic treatment of parkinsonism.
Biobamat
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Biobamat
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Biobamat
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Biobamat
Patient Information
Biobamat
Organisms Affected
Humans and other mammals