Atraxin
Brand names,
Atraxin
Analogs
Atraxin
Brand Names Mixture
Atraxin
Chemical_Formula
C20H23NS
Atraxin
RX_link
No information avaliable
Atraxin
fda sheet
Atraxin
msds (material safety sheet)
Atraxin
Synthesis Reference
No information avaliable
Atraxin
Molecular Weight
309.469 g/mol
Atraxin
Melting Point
< 25 oC
Atraxin
H2O Solubility
Soluble as HCl salt
Atraxin
State
Liquid
Atraxin
LogP
5.7
Atraxin
Dosage Forms
Tablets (oral, 1 mg)
Atraxin
Indication
Used for the symptomatic treatment of parkinsonism.
Atraxin
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Atraxin
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Atraxin
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Atraxin
Patient Information
Atraxin
Organisms Affected
Humans and other mammals