Artolon
Brand names,
Artolon
Analogs
Artolon
Brand Names Mixture
Artolon
Chemical_Formula
C20H23NS
Artolon
RX_link
No information avaliable
Artolon
fda sheet
Artolon
msds (material safety sheet)
Artolon
Synthesis Reference
No information avaliable
Artolon
Molecular Weight
309.469 g/mol
Artolon
Melting Point
< 25 oC
Artolon
H2O Solubility
Soluble as HCl salt
Artolon
State
Liquid
Artolon
LogP
5.7
Artolon
Dosage Forms
Tablets (oral, 1 mg)
Artolon
Indication
Used for the symptomatic treatment of parkinsonism.
Artolon
Pharmacology
Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.
Artolon
Absorption
Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.
Artolon
side effects and Toxicity
Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Artolon
Patient Information
Artolon
Organisms Affected
Humans and other mammals