Metixene

Metixene Brand names, Metixene Analogs

Metixene Brand Names Mixture

No information avaliable

Metixene Chemical_Formula

C₂₀H₂₃NS

Metixene RX_link

No information avaliable

Metixene fda sheet

Metixene msds (material safety sheet)

Metixene Synthesis Reference

No information avaliable

Metixene Molecular Weight

309.469 g/mol

Metixene Melting Point

< 25 ^oC

Metixene H₂O Solubility

Soluble as HCl salt

Metixene State

Liquid

Metixene LogP

5.7

Metixene Dosage Forms

Tablets (oral, 1 mg)

Metixene Indication

Used for the symptomatic treatment of parkinsonism.

Metixene Pharmacology

Metixene is a tertiary antimuscarinic with actions similar to those of atropine; it also has antihistaminic and direct antispasmodic properties. It is used for the symptomatic treatment of parkinsonism, including the alleviation of the extrapyramidal syndrome induced by other drugs such as phenothiazines, but, like other antimuscarinics, it is of no value against tardive dyskinesias. Metixene has been discontinued.

Metixene Absorption

Absorbed in the gastrointestinal tract following oral administration, however the extent of absorption is not known.

Metixene side effects and Toxicity

Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Metixene Patient Information

Metixene Organisms Affected

Humans and other mammals