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Mephabutazone Brand names, Mephabutazone Analogs

Mephabutazone Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Mephabutazone Chemical_Formula


Mephabutazone RX_link

No information avaliable

Mephabutazone fda sheet

Mephabutazone msds (material safety sheet)

Mephabutazone MSDS

Mephabutazone Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Mephabutazone Molecular Weight

308.374 g/mol

Mephabutazone Melting Point

105 oC

Mephabutazone H2O Solubility

47.5 mg/L

Mephabutazone State


Mephabutazone LogP


Mephabutazone Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Mephabutazone Indication

For the treatment of backache and ankylosing spondylitis

Mephabutazone Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Mephabutazone Absorption

No information avaliable

Mephabutazone side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Mephabutazone Patient Information

No information avaliable

Mephabutazone Organisms Affected

Humans and other mammals