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Ecobutazone Brand names, Ecobutazone Analogs

Ecobutazone Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Ecobutazone Chemical_Formula


Ecobutazone RX_link

No information avaliable

Ecobutazone fda sheet

Ecobutazone msds (material safety sheet)

Ecobutazone MSDS

Ecobutazone Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Ecobutazone Molecular Weight

308.374 g/mol

Ecobutazone Melting Point

105 oC

Ecobutazone H2O Solubility

47.5 mg/L

Ecobutazone State


Ecobutazone LogP


Ecobutazone Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Ecobutazone Indication

For the treatment of backache and ankylosing spondylitis

Ecobutazone Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Ecobutazone Absorption

No information avaliable

Ecobutazone side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Ecobutazone Patient Information

No information avaliable

Ecobutazone Organisms Affected

Humans and other mammals