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Ambene Brand names, Ambene Analogs

Ambene Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Ambene Chemical_Formula


Ambene RX_link

No information avaliable

Ambene fda sheet

Ambene msds (material safety sheet)

Ambene MSDS

Ambene Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Ambene Molecular Weight

308.374 g/mol

Ambene Melting Point

105 oC

Ambene H2O Solubility

47.5 mg/L

Ambene State


Ambene LogP


Ambene Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Ambene Indication

For the treatment of backache and ankylosing spondylitis

Ambene Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Ambene Absorption

No information avaliable

Ambene side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Ambene Patient Information

No information avaliable

Ambene Organisms Affected

Humans and other mammals