Butaluy
Brand names,
Butaluy
Analogs
Butaluy
Brand Names Mixture
- Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
- Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
- Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
Butaluy
Chemical_Formula
C19H20N2O2
Butaluy
RX_link
No information avaliable
Butaluy
fda sheet
Butaluy
msds (material safety sheet)
Butaluy
Synthesis Reference
Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)
Butaluy
Molecular Weight
308.374 g/mol
Butaluy
Melting Point
105 oC
Butaluy
H2O Solubility
47.5 mg/L
Butaluy
State
Solid
Butaluy
LogP
4.214
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Dosage Forms
Bolus; Liquid; Paste; Powder; Solution; Tablet
Butaluy
Indication
For the treatment of backache and ankylosing spondylitis
Butaluy
Pharmacology
Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation
Butaluy
Absorption
No information avaliable
Butaluy
side effects and Toxicity
Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)
Butaluy
Patient Information
No information avaliable
Butaluy
Organisms Affected
Humans and other mammals