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Rectofasa Brand names, Rectofasa Analogs

Rectofasa Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Rectofasa Chemical_Formula

C19H20N2O2

Rectofasa RX_link

No information avaliable

Rectofasa fda sheet

Rectofasa msds (material safety sheet)

Rectofasa MSDS

Rectofasa Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Rectofasa Molecular Weight

308.374 g/mol

Rectofasa Melting Point

105 oC

Rectofasa H2O Solubility

47.5 mg/L

Rectofasa State

Solid

Rectofasa LogP

4.214

Rectofasa Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Rectofasa Indication

For the treatment of backache and ankylosing spondylitis

Rectofasa Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Rectofasa Absorption

No information avaliable

Rectofasa side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Rectofasa Patient Information

No information avaliable

Rectofasa Organisms Affected

Humans and other mammals