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Phenylbutaz Brand names, Phenylbutaz Analogs

Phenylbutaz Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Phenylbutaz Chemical_Formula


Phenylbutaz RX_link

No information avaliable

Phenylbutaz fda sheet

Phenylbutaz msds (material safety sheet)

Phenylbutaz MSDS

Phenylbutaz Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Phenylbutaz Molecular Weight

308.374 g/mol

Phenylbutaz Melting Point

105 oC

Phenylbutaz H2O Solubility

47.5 mg/L

Phenylbutaz State


Phenylbutaz LogP


Phenylbutaz Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Phenylbutaz Indication

For the treatment of backache and ankylosing spondylitis

Phenylbutaz Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Phenylbutaz Absorption

No information avaliable

Phenylbutaz side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Phenylbutaz Patient Information

No information avaliable

Phenylbutaz Organisms Affected

Humans and other mammals