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Intrazone Brand names, Intrazone Analogs

Intrazone Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Intrazone Chemical_Formula


Intrazone RX_link

No information avaliable

Intrazone fda sheet

Intrazone msds (material safety sheet)

Intrazone MSDS

Intrazone Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Intrazone Molecular Weight

308.374 g/mol

Intrazone Melting Point

105 oC

Intrazone H2O Solubility

47.5 mg/L

Intrazone State


Intrazone LogP


Intrazone Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Intrazone Indication

For the treatment of backache and ankylosing spondylitis

Intrazone Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Intrazone Absorption

No information avaliable

Intrazone side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Intrazone Patient Information

No information avaliable

Intrazone Organisms Affected

Humans and other mammals