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Schemergin Brand names, Schemergin Analogs

Schemergin Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Schemergin Chemical_Formula

C19H20N2O2

Schemergin RX_link

No information avaliable

Schemergin fda sheet

Schemergin msds (material safety sheet)

Schemergin MSDS

Schemergin Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Schemergin Molecular Weight

308.374 g/mol

Schemergin Melting Point

105 oC

Schemergin H2O Solubility

47.5 mg/L

Schemergin State

Solid

Schemergin LogP

4.214

Schemergin Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Schemergin Indication

For the treatment of backache and ankylosing spondylitis

Schemergin Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Schemergin Absorption

No information avaliable

Schemergin side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Schemergin Patient Information

No information avaliable

Schemergin Organisms Affected

Humans and other mammals