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Zorane Brand names, Zorane Analogs

Zorane Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Zorane Chemical_Formula


Zorane RX_link

No information avaliable

Zorane fda sheet

Zorane msds (material safety sheet)

Zorane MSDS

Zorane Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Zorane Molecular Weight

308.374 g/mol

Zorane Melting Point

105 oC

Zorane H2O Solubility

47.5 mg/L

Zorane State


Zorane LogP


Zorane Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Zorane Indication

For the treatment of backache and ankylosing spondylitis

Zorane Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Zorane Absorption

No information avaliable

Zorane side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Zorane Patient Information

No information avaliable

Zorane Organisms Affected

Humans and other mammals