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Butalan Brand names, Butalan Analogs

Butalan Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Butalan Chemical_Formula


Butalan RX_link

No information avaliable

Butalan fda sheet

Butalan msds (material safety sheet)

Butalan MSDS

Butalan Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Butalan Molecular Weight

308.374 g/mol

Butalan Melting Point

105 oC

Butalan H2O Solubility

47.5 mg/L

Butalan State


Butalan LogP


Butalan Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Butalan Indication

For the treatment of backache and ankylosing spondylitis

Butalan Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Butalan Absorption

No information avaliable

Butalan side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Butalan Patient Information

No information avaliable

Butalan Organisms Affected

Humans and other mammals