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Phenylbutazonum Brand names, Phenylbutazonum Analogs

Phenylbutazonum Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Phenylbutazonum Chemical_Formula


Phenylbutazonum RX_link

No information avaliable

Phenylbutazonum fda sheet

Phenylbutazonum msds (material safety sheet)

Phenylbutazonum MSDS

Phenylbutazonum Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Phenylbutazonum Molecular Weight

308.374 g/mol

Phenylbutazonum Melting Point

105 oC

Phenylbutazonum H2O Solubility

47.5 mg/L

Phenylbutazonum State


Phenylbutazonum LogP


Phenylbutazonum Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Phenylbutazonum Indication

For the treatment of backache and ankylosing spondylitis

Phenylbutazonum Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Phenylbutazonum Absorption

No information avaliable

Phenylbutazonum side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Phenylbutazonum Patient Information

No information avaliable

Phenylbutazonum Organisms Affected

Humans and other mammals