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Butagesic Brand names, Butagesic Analogs

Butagesic Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Butagesic Chemical_Formula


Butagesic RX_link

No information avaliable

Butagesic fda sheet

Butagesic msds (material safety sheet)

Butagesic MSDS

Butagesic Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Butagesic Molecular Weight

308.374 g/mol

Butagesic Melting Point

105 oC

Butagesic H2O Solubility

47.5 mg/L

Butagesic State


Butagesic LogP


Butagesic Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Butagesic Indication

For the treatment of backache and ankylosing spondylitis

Butagesic Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Butagesic Absorption

No information avaliable

Butagesic side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Butagesic Patient Information

No information avaliable

Butagesic Organisms Affected

Humans and other mammals