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Diphebuzol Brand names, Diphebuzol Analogs

Diphebuzol Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Diphebuzol Chemical_Formula


Diphebuzol RX_link

No information avaliable

Diphebuzol fda sheet

Diphebuzol msds (material safety sheet)

Diphebuzol MSDS

Diphebuzol Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Diphebuzol Molecular Weight

308.374 g/mol

Diphebuzol Melting Point

105 oC

Diphebuzol H2O Solubility

47.5 mg/L

Diphebuzol State


Diphebuzol LogP


Diphebuzol Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Diphebuzol Indication

For the treatment of backache and ankylosing spondylitis

Diphebuzol Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Diphebuzol Absorption

No information avaliable

Diphebuzol side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Diphebuzol Patient Information

No information avaliable

Diphebuzol Organisms Affected

Humans and other mammals