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Butarecbon Brand names, Butarecbon Analogs

Butarecbon Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Butarecbon Chemical_Formula

C19H20N2O2

Butarecbon RX_link

No information avaliable

Butarecbon fda sheet

Butarecbon msds (material safety sheet)

Butarecbon MSDS

Butarecbon Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Butarecbon Molecular Weight

308.374 g/mol

Butarecbon Melting Point

105 oC

Butarecbon H2O Solubility

47.5 mg/L

Butarecbon State

Solid

Butarecbon LogP

4.214

Butarecbon Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Butarecbon Indication

For the treatment of backache and ankylosing spondylitis

Butarecbon Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Butarecbon Absorption

No information avaliable

Butarecbon side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Butarecbon Patient Information

No information avaliable

Butarecbon Organisms Affected

Humans and other mammals