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Fenylbutazon Brand names, Fenylbutazon Analogs

Fenylbutazon Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Fenylbutazon Chemical_Formula


Fenylbutazon RX_link

No information avaliable

Fenylbutazon fda sheet

Fenylbutazon msds (material safety sheet)

Fenylbutazon MSDS

Fenylbutazon Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Fenylbutazon Molecular Weight

308.374 g/mol

Fenylbutazon Melting Point

105 oC

Fenylbutazon H2O Solubility

47.5 mg/L

Fenylbutazon State


Fenylbutazon LogP


Fenylbutazon Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Fenylbutazon Indication

For the treatment of backache and ankylosing spondylitis

Fenylbutazon Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Fenylbutazon Absorption

No information avaliable

Fenylbutazon side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Fenylbutazon Patient Information

No information avaliable

Fenylbutazon Organisms Affected

Humans and other mammals