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Shigrodin Brand names, Shigrodin Analogs

Shigrodin Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Shigrodin Chemical_Formula


Shigrodin RX_link

No information avaliable

Shigrodin fda sheet

Shigrodin msds (material safety sheet)

Shigrodin MSDS

Shigrodin Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Shigrodin Molecular Weight

308.374 g/mol

Shigrodin Melting Point

105 oC

Shigrodin H2O Solubility

47.5 mg/L

Shigrodin State


Shigrodin LogP


Shigrodin Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Shigrodin Indication

For the treatment of backache and ankylosing spondylitis

Shigrodin Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Shigrodin Absorption

No information avaliable

Shigrodin side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Shigrodin Patient Information

No information avaliable

Shigrodin Organisms Affected

Humans and other mammals