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Artrizone Brand names, Artrizone Analogs

Artrizone Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Artrizone Chemical_Formula


Artrizone RX_link

No information avaliable

Artrizone fda sheet

Artrizone msds (material safety sheet)

Artrizone MSDS

Artrizone Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Artrizone Molecular Weight

308.374 g/mol

Artrizone Melting Point

105 oC

Artrizone H2O Solubility

47.5 mg/L

Artrizone State


Artrizone LogP


Artrizone Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Artrizone Indication

For the treatment of backache and ankylosing spondylitis

Artrizone Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Artrizone Absorption

No information avaliable

Artrizone side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Artrizone Patient Information

No information avaliable

Artrizone Organisms Affected

Humans and other mammals