Artizin en es it fr

Artizin Brand names, Artizin Analogs

Artizin Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Artizin Chemical_Formula


Artizin RX_link

No information avaliable

Artizin fda sheet

Artizin msds (material safety sheet)

Artizin MSDS

Artizin Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Artizin Molecular Weight

308.374 g/mol

Artizin Melting Point

105 oC

Artizin H2O Solubility

47.5 mg/L

Artizin State


Artizin LogP


Artizin Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Artizin Indication

For the treatment of backache and ankylosing spondylitis

Artizin Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Artizin Absorption

No information avaliable

Artizin side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Artizin Patient Information

No information avaliable

Artizin Organisms Affected

Humans and other mammals