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Busone Brand names, Busone Analogs

Busone Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Busone Chemical_Formula


Busone RX_link

No information avaliable

Busone fda sheet

Busone msds (material safety sheet)

Busone MSDS

Busone Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Busone Molecular Weight

308.374 g/mol

Busone Melting Point

105 oC

Busone H2O Solubility

47.5 mg/L

Busone State


Busone LogP


Busone Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Busone Indication

For the treatment of backache and ankylosing spondylitis

Busone Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Busone Absorption

No information avaliable

Busone side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Busone Patient Information

No information avaliable

Busone Organisms Affected

Humans and other mammals