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Butadiona Brand names, Butadiona Analogs

Butadiona Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Butadiona Chemical_Formula


Butadiona RX_link

No information avaliable

Butadiona fda sheet

Butadiona msds (material safety sheet)

Butadiona MSDS

Butadiona Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Butadiona Molecular Weight

308.374 g/mol

Butadiona Melting Point

105 oC

Butadiona H2O Solubility

47.5 mg/L

Butadiona State


Butadiona LogP


Butadiona Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Butadiona Indication

For the treatment of backache and ankylosing spondylitis

Butadiona Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Butadiona Absorption

No information avaliable

Butadiona side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Butadiona Patient Information

No information avaliable

Butadiona Organisms Affected

Humans and other mammals