Phenbutazol en es it fr

Phenbutazol Brand names, Phenbutazol Analogs

Phenbutazol Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Phenbutazol Chemical_Formula


Phenbutazol RX_link

No information avaliable

Phenbutazol fda sheet

Phenbutazol msds (material safety sheet)

Phenbutazol MSDS

Phenbutazol Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Phenbutazol Molecular Weight

308.374 g/mol

Phenbutazol Melting Point

105 oC

Phenbutazol H2O Solubility

47.5 mg/L

Phenbutazol State


Phenbutazol LogP


Phenbutazol Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Phenbutazol Indication

For the treatment of backache and ankylosing spondylitis

Phenbutazol Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Phenbutazol Absorption

No information avaliable

Phenbutazol side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Phenbutazol Patient Information

No information avaliable

Phenbutazol Organisms Affected

Humans and other mammals