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Novophenyl Brand names, Novophenyl Analogs

Novophenyl Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Novophenyl Chemical_Formula

C19H20N2O2

Novophenyl RX_link

No information avaliable

Novophenyl fda sheet

Novophenyl msds (material safety sheet)

Novophenyl MSDS

Novophenyl Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Novophenyl Molecular Weight

308.374 g/mol

Novophenyl Melting Point

105 oC

Novophenyl H2O Solubility

47.5 mg/L

Novophenyl State

Solid

Novophenyl LogP

4.214

Novophenyl Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Novophenyl Indication

For the treatment of backache and ankylosing spondylitis

Novophenyl Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Novophenyl Absorption

No information avaliable

Novophenyl side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Novophenyl Patient Information

No information avaliable

Novophenyl Organisms Affected

Humans and other mammals