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Tazone Brand names, Tazone Analogs

Tazone Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Tazone Chemical_Formula


Tazone RX_link

No information avaliable

Tazone fda sheet

Tazone msds (material safety sheet)

Tazone MSDS

Tazone Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Tazone Molecular Weight

308.374 g/mol

Tazone Melting Point

105 oC

Tazone H2O Solubility

47.5 mg/L

Tazone State


Tazone LogP


Tazone Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Tazone Indication

For the treatment of backache and ankylosing spondylitis

Tazone Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Tazone Absorption

No information avaliable

Tazone side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Tazone Patient Information

No information avaliable

Tazone Organisms Affected

Humans and other mammals