Phebuzin en es it fr

Phebuzin Brand names, Phebuzin Analogs

Phebuzin Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Phebuzin Chemical_Formula


Phebuzin RX_link

No information avaliable

Phebuzin fda sheet

Phebuzin msds (material safety sheet)

Phebuzin MSDS

Phebuzin Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Phebuzin Molecular Weight

308.374 g/mol

Phebuzin Melting Point

105 oC

Phebuzin H2O Solubility

47.5 mg/L

Phebuzin State


Phebuzin LogP


Phebuzin Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Phebuzin Indication

For the treatment of backache and ankylosing spondylitis

Phebuzin Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Phebuzin Absorption

No information avaliable

Phebuzin side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Phebuzin Patient Information

No information avaliable

Phebuzin Organisms Affected

Humans and other mammals