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Azobutyl Brand names, Azobutyl Analogs

Azobutyl Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Azobutyl Chemical_Formula

C19H20N2O2

Azobutyl RX_link

No information avaliable

Azobutyl fda sheet

Azobutyl msds (material safety sheet)

Azobutyl MSDS

Azobutyl Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Azobutyl Molecular Weight

308.374 g/mol

Azobutyl Melting Point

105 oC

Azobutyl H2O Solubility

47.5 mg/L

Azobutyl State

Solid

Azobutyl LogP

4.214

Azobutyl Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Azobutyl Indication

For the treatment of backache and ankylosing spondylitis

Azobutyl Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Azobutyl Absorption

No information avaliable

Azobutyl side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Azobutyl Patient Information

No information avaliable

Azobutyl Organisms Affected

Humans and other mammals