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Butadion Brand names, Butadion Analogs

Butadion Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Butadion Chemical_Formula


Butadion RX_link

No information avaliable

Butadion fda sheet

Butadion msds (material safety sheet)

Butadion MSDS

Butadion Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Butadion Molecular Weight

308.374 g/mol

Butadion Melting Point

105 oC

Butadion H2O Solubility

47.5 mg/L

Butadion State


Butadion LogP


Butadion Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Butadion Indication

For the treatment of backache and ankylosing spondylitis

Butadion Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Butadion Absorption

No information avaliable

Butadion side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Butadion Patient Information

No information avaliable

Butadion Organisms Affected

Humans and other mammals