Reumazin en es it fr

Reumazin Brand names, Reumazin Analogs

Reumazin Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Reumazin Chemical_Formula


Reumazin RX_link

No information avaliable

Reumazin fda sheet

Reumazin msds (material safety sheet)

Reumazin MSDS

Reumazin Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Reumazin Molecular Weight

308.374 g/mol

Reumazin Melting Point

105 oC

Reumazin H2O Solubility

47.5 mg/L

Reumazin State


Reumazin LogP


Reumazin Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Reumazin Indication

For the treatment of backache and ankylosing spondylitis

Reumazin Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Reumazin Absorption

No information avaliable

Reumazin side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Reumazin Patient Information

No information avaliable

Reumazin Organisms Affected

Humans and other mammals