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Artrizin Brand names, Artrizin Analogs

Artrizin Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Artrizin Chemical_Formula


Artrizin RX_link

No information avaliable

Artrizin fda sheet

Artrizin msds (material safety sheet)

Artrizin MSDS

Artrizin Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Artrizin Molecular Weight

308.374 g/mol

Artrizin Melting Point

105 oC

Artrizin H2O Solubility

47.5 mg/L

Artrizin State


Artrizin LogP


Artrizin Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Artrizin Indication

For the treatment of backache and ankylosing spondylitis

Artrizin Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Artrizin Absorption

No information avaliable

Artrizin side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Artrizin Patient Information

No information avaliable

Artrizin Organisms Affected

Humans and other mammals