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Benzone Brand names, Benzone Analogs

Benzone Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Benzone Chemical_Formula


Benzone RX_link

No information avaliable

Benzone fda sheet

Benzone msds (material safety sheet)

Benzone MSDS

Benzone Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Benzone Molecular Weight

308.374 g/mol

Benzone Melting Point

105 oC

Benzone H2O Solubility

47.5 mg/L

Benzone State


Benzone LogP


Benzone Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Benzone Indication

For the treatment of backache and ankylosing spondylitis

Benzone Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Benzone Absorption

No information avaliable

Benzone side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Benzone Patient Information

No information avaliable

Benzone Organisms Affected

Humans and other mammals