Robizone-V en es it fr

Robizone-V Brand names, Robizone-V Analogs

Robizone-V Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Robizone-V Chemical_Formula


Robizone-V RX_link

No information avaliable

Robizone-V fda sheet

Robizone-V msds (material safety sheet)

Robizone-V MSDS

Robizone-V Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Robizone-V Molecular Weight

308.374 g/mol

Robizone-V Melting Point

105 oC

Robizone-V H2O Solubility

47.5 mg/L

Robizone-V State


Robizone-V LogP


Robizone-V Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Robizone-V Indication

For the treatment of backache and ankylosing spondylitis

Robizone-V Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Robizone-V Absorption

No information avaliable

Robizone-V side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Robizone-V Patient Information

No information avaliable

Robizone-V Organisms Affected

Humans and other mammals