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Praecirheumin Brand names, Praecirheumin Analogs

Praecirheumin Brand Names Mixture

  • Alka Phenyl Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Alka Phenylbutazone Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)
  • Phenylone Plus Tab (Aluminum Hydroxide + Magnesium Trisilicate + Phenylbutazone)

Praecirheumin Chemical_Formula


Praecirheumin RX_link

No information avaliable

Praecirheumin fda sheet

Praecirheumin msds (material safety sheet)

Praecirheumin MSDS

Praecirheumin Synthesis Reference

Ullmann's Encyklopaedie der Technischen Chemie 13, 298 (1962)

Praecirheumin Molecular Weight

308.374 g/mol

Praecirheumin Melting Point

105 oC

Praecirheumin H2O Solubility

47.5 mg/L

Praecirheumin State


Praecirheumin LogP


Praecirheumin Dosage Forms

Bolus; Liquid; Paste; Powder; Solution; Tablet

Praecirheumin Indication

For the treatment of backache and ankylosing spondylitis

Praecirheumin Pharmacology

Phenylbutazone is a synthetic, pyrazolone derivative. It is a nonhormonal anti-inflammatory, antipyretic compound useful in the management of inflammatory conditions. The apparent analgesic effect is probably related mainly to the compound's anti-inflammatory properties and arise from its ability to reduce production of prostaglandin H and prostacyclin. Prostaglandins act on a variety of cells such as vascular smooth muscle cells causing constriction or dilation, on platelets causing aggregation or disaggregation and on spinal neurons causing pain. Prostacylcin causes vascular constriction platelet disaggregation

Praecirheumin Absorption

No information avaliable

Praecirheumin side effects and Toxicity

Oral, LD50 = 238 mg/kg (mouse); Oral, LD50 = 781 mg/kg (rabbit); Oral, LD50 = 245 mg/kg (rat); Oral, LD50 = 375 mg/kg (rat)

Praecirheumin Patient Information

No information avaliable

Praecirheumin Organisms Affected

Humans and other mammals